Associate Professor, Zhejiang university, China
Lidan Hu is a Distinguished Associate Research Fellow at the National Clinical Research Center of the Children’s Hospital Affiliated to Zhejiang University School of Medicine. She obtained her doctoral degree from Tsinghua University and later pursued postdoctoral research at the same institution. Her research primarily focuses on kidney disease, RNA metabolism, and genetic disorders, contributing significantly to medical science. She has received multiple awards for her innovative contributions and teaching excellence. Her work has been widely recognized in top-tier journals, covering topics like protein aggregation in cataracts, stress granules in neurological disorders, and cholesterol metabolism. Through her research, she has made groundbreaking advancements in enzyme activity and molecular mechanisms related to human diseases.
PROFESSIONAL PROFILE
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STRENGTHS FOR THE AWARD
Lidan Hu has demonstrated outstanding contributions to biomedical research, particularly in the fields of RNA metabolism, genetic diseases, and kidney-related studies. His significant work on lanosterolβs role in reversing protein aggregation in cataracts, as published in Nature, has received over 500 citations, showcasing its high impact. His research extends to cholesterol metabolism, stress granules, and viral infections, highlighting a diverse expertise in molecular biology and clinical applications. Additionally, his consistent publication record in high-impact journals and recognition through awards, including the Special Contribution Award – Innovation Award (2022) and the China Postdoctoral Science Foundation First-Class Funding (2017), further attest to his excellence.
AREAS FOR IMPROVEMENT
While Dr. Huβs research contributions are substantial, an increased focus on clinical applications and translational research could enhance the direct impact of his findings on patient care. Additionally, further leadership roles in large-scale research collaborations or international projects could strengthen his global recognition.
EDUCATION π
π 2012.08β2017.07 β Tsinghua University (Doctoral Degree)
π 2017.08β2020.07 β Postdoctoral Researcher, Tsinghua University
Lidan Hu earned her Ph.D. from Tsinghua University, where she focused on molecular biology, enzyme activity, and genetic disorders. During her postdoctoral research, she deepened her expertise in RNA metabolism and disease mechanisms. Her education laid a strong foundation for her contributions in clinical research, particularly in areas related to neurological disorders and metabolic diseases.
WORK EXPERIENCE πΌ
π 2020.08βPresent β Distinguished Associate Research Fellow, National Clinical Research Center of the Children’s Hospital Affiliated to Zhejiang University School of Medicine
π 2017.08β2020.07 β Postdoctoral Researcher, Tsinghua University
Lidan Hu’s career has been marked by significant contributions to medical research, particularly in protein aggregation, metabolic disorders, and pediatric health. She currently works at Zhejiang University School of Medicine, where she plays a crucial role in clinical and translational research. Her expertise spans molecular mechanisms in kidney disease, stress granules, and enzyme activity, with numerous publications in prestigious journals.
AWARDS AND HONORS π
π 2022 Special Contribution Award β Innovation Award, Zhejiang University
π 2022 Third Prize β Young Teacher Teaching Competition, Zhejiang University
π 2022 Excellent Social Practice Team β Zhejiang University Level
π 2017 First-Class Funding β China Postdoctoral Science Foundation
π 2017 First Prize β Poster Presentation at the National Enzymology Conference
These awards highlight her excellence in research, innovation, and teaching. Her groundbreaking discoveries in cataracts, enzyme mechanisms, and metabolic diseases have been widely acknowledged.
RESEARCH FOCUS π¬
𧬠RNA Metabolism β Studying the role of RNA in genetic diseases and cellular mechanisms.
π¬ Genetic Disease β Investigating mutation-driven disorders and their impact on human health.
π Cataracts & Protein Aggregation β Exploring lanosterol’s effect on cataract-causing proteins.
π§ͺ Cholesterol Metabolism β Understanding how cholesterol affects cellular processes and diseases.
π§ Stress Granules & Neurological Disorders β Studying their role in ALS and spinal muscular atrophy.
π Clinical Applications β Translating findings into medical treatments for metabolic diseases.
Her research has led to breakthroughs in enzyme activity, disease modeling, and biomolecular interactions.
PUBLICATION TOP NOTESΒ π
π Lanosterol reverses protein aggregation in cataracts β Nature
π Lanosterol and 25-hydroxycholesterol dissociate crystallin aggregates β Biochemical and Biophysical Research Communications
π Cataract-causing mutation S228P promotes Ξ²B1-crystallin aggregation β Protein & Cell
π Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes β BBA-Molecular Cell Research
π Multiple functions of stress granules in viral infection at a glance β Frontiers in Microbiology
π Cholesterol metabolism: Physiological regulation and diseases β MedComm
π Screening novel stress granule regulators from a natural compound library β Protein & Cell
π A review of inactivated COVID-19 vaccine development in China β Vaccines
π Stress granules in spinal muscular atrophy and ALS β Neurobiology of Disease
π Epidemiological characteristics of respiratory syncytial virus infection in pediatric patients β Journal of Medical Virology
Her highly cited research has been pivotal in understanding molecular mechanisms in various diseases.
CONCLUSION
Lidan Huβs exceptional research contributions, highly cited publications, and academic accolades make him a strong candidate for the Best Researcher Award. His work has significantly advanced understanding in biomedical sciences, particularly in protein aggregation diseases, stress granules, and metabolic disorders, aligning with the award’s criteria for impactful and innovative research.